According to data, among the serious adverse reactions there are 129 cases of death among people with a median age of 77 years, according to the Pharmacovigilance Report.

The document notes, however, that these deaths cannot be considered related to a vaccine against Covid-19 just because they were spontaneously notified to the National Pharmacovigilance System.

In most of the reported cases and with more information, it is said in the document, the death can be explained by the patient's medical history and/or other treatments.

According to the report, a total of 23,667,634 vaccines were administered by the end of March.

Most adverse reactions (12,426) are related to the Pfizer/BioNtech (Comirnaty) vaccine, followed by AstraZeneca (Vaxzevria), with 6,324, Moderna (Spikevax), with 3,294, and Janssen, with 3,294.

Infarmed stresses, however, that these data "do not allow the comparison of safety profiles between vaccines", since they were used in different population subgroups (age, gender, health profile, among others) and "in periods and epidemiological contexts distinct".

Of the cases of adverse reactions classified as serious, "about 85% concern situations of temporary incapacity (including absenteeism from work)".

Of the serious adverse reactions, the report says that 4,640 (19.2%) were classified as clinically important, 1,919 (8%) caused some disability, 833 (3.5%) required hospitalization, 270 (1.1%) represented life-threatening and 129 (0.5%) resulted in death.

By age group, those between 25 and 49 years old registered the most cases of serious adverse effects (3,621 cases), which also had the highest number of vaccines administered (7,740,606).