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Cluster headaches may be more common in men, but are more severe in women, according to new research.

These are short, painful headaches occurring in a row – sometimes for many days or weeks, and lasting between 15 minutes and three hours.

A new study from the Karolinska Institutet in Stockholm, Sweden, surveyed 874 people diagnosed with cluster headaches, with 66% male and 34% female. It found 18% of women were diagnosed with chronic cluster headaches, compared to 9% of men, with attacks also lasting longer for women.

Here’s everything you need to know about cluster headaches…

What are cluster headaches?

“Cluster headaches are, for most people, an extremely severe headache disorder,” explains Dr Nicholas Silver, consultant neurologist at The Walton Centre NHS Foundation Trust.

“It typically causes unilateral attacks – on just one side of the head – with severe pain, a sense of restlessness and agitation and prominent puffy, droopy, red eyes, tearing, stuffy or runny nose, flushing, sweating, a sense of fullness in the ear or tinnitus.

“Attacks are sometimes triggered very quickly by even tiny amounts of alcohol. The condition often causes severe mood disturbance and can lead to suicidal thoughts.”

Speak to your GP if you are concerned about any of these symptoms.

Do they follow a pattern?

“Cluster headache may be episodic, causing recurrent attacks over weeks to months,” says Silver. They are often classed as chronic when “attacks are ongoing without a significant break for over a year”.

Silver also suggests the time of the year could play a part, as bouts “are more likely to occur at certain times of the year – for example, spring or autumn”.

He continues: “It is thought that an area of the brain called the hypothalamus is involved in generating the symptoms of cluster headache, and this area has clock-like functions – which may explain why cluster bouts may be seasonal, and may be induced by travelling long distances across time zones, as well as explaining why attacks of pain may occur commonly at certain times of the day.”

Who might get them?

“Cluster headaches tend to affect men more than women, with 70% of those affected being male,” suggests Dr Simon Erridge, head of research and access at Sapphire Medical Clinic.

“The peak of onset of cluster headache is between 20-40 years of age, before reducing in incidence in later years of life.”

Silver adds it is also more common “in smokers than non-smokers”, and “is only rarely noted to run in families as a genetic disorder”.

How can they be treated?

“It is always important to consult a health professional for a full evaluation,” says Erridge.

“However, whilst awaiting this, it is really useful to consider if there are any triggers or exacerbating factors which make the headaches more likely. For cluster headaches, two key factors that people can do to improve the likelihood of improving their symptoms is reducing or stopping smoking and drinking alcohol.”

According to the NHS, over-the-counter medication like paracetamol isn’t effective in treating cluster headaches.

“Patients with cluster headaches should be referred to a neurologist,” advises Silver.

“To treat individual attacks we give sumatriptan 3mg injections – up to four injections a day using a special auto-injector into the thigh. A high flow 100% oxygen through a sealed mask with no holes in it may be helpful, and delivery with a demand valve similar to that used for ‘gas and air’ in labour is often far more effective and safer,” Silver explains.

“As neurologists, we also have a number of other advanced therapies which can be very effective. Patients [may] need mental health support to help them at worse times, although the main treatment will be to just reduce the headaches.”

However, Erridge adds: “There [may be] a need for further options for patients as a number of patients still suffer. These include surgical options and emerging medications, such as medical cannabis, which can be prescribed for individuals who have not satisfactorily responded to two or more first-line treatments.”